The Izotropic Breast Imaging System provides true 3-D imaging with a 360° view acquisition. With breast CT, identifying tumors and determining their size, shape, location and depth is made easier with multiple viewpoints.
Results of images taken on hundreds of patients during clinical trials at UC Davis Medical Center show that the most recent model of the Izotropic Breast Imaging System is superior to the current modalities when used with contrast.
The Izotropic Breast Imaging Platform is also unlike widely available whole-body computed tomography systems that circle a patient’s body to collect images of interest. Instead, breast CT makes use of cone-beam computed tomography technology to scan only the breast of interest.
With breast CT, the woman lays face down on the system table placing the breast to be imaged in a hole in the table. The imaging hardware beneath the table circles around the breast creating a series of raw-data images. The platform computer processes these raw images to reconstruct true three-dimensional, high-resolution images, allowing radiologists to view the breast anatomy from any angle.
The Breast Cancer Landscape
Global Breast Cancer Diagnoses Each Year
Global Deaths From Breast Cancer
2019 Projected USA Breast Cancer Deaths
2019 Projected Breast Cancer Cases in the USA
There’s an urgent need for a cost-effective screening method that offers greater accuracy, speed, and comfort.
The medical community is very aware of current limitations in detecting breast cancer. Doctors are using the additional breast imaging modalities with increasing frequency, and researchers are actively pursuing new detection advances.
Mammography vs Breast CT
Digital mammography, the current standard for breast cancer screening, misses one in five breast cancers (false-negative results). Stress-inducing false-positive results are also common. Both traditional digital mammography and digital tomosynthesis, which is sometimes marketed as 3-D mammography, are two-dimensional imaging technologies.
In the USA, the Mammography Quality Standards Act (MQSA), enacted October 27, 1992, ensures that all women have access to quality mammography for the detection of breast cancer in its earliest and most treatable stages. As of October 1, 2018, there are a total of 8,622 MSQA certified facilities and 20,303 accredited units in the USA.
Despite the success of mammography in driving down breast cancer mortality since its widespread introduction in the late 1980s, screening mammography is not an ideal test for the following reasons:
Misses approximately one in five breast cancers*
May fail to detect inflammatory breast cancer, the deadliest form of breast cancer
50% of women who get annual mammograms over a 10-year period* will have a false-positive finding at least once.
Requires painful breast compression and technologist handling of the woman’s breast.
Provides lower diagnostic accuracy and risks implant rupture in women with breast implants
*According to the National Cancer Institute
For these reasons, the breast imaging community continues to look for a cost-effective, true 3-D breast imaging technology that improves patient comfort and delivers high diagnostic accuracy.
In this standard two-view mammogram of a patient with breast implants, the cancer mass is obscured.
Here, the breast cancer mass and microcalcifications present are clearly visible.
Advantages Over Existing Technologies
Mammography is a 2-D technology. Tomosynthesis, sometimes errantly referred to as 3- D mammography, improves on this only slightly. While breast ultrasound examinations and MRI breast imaging provide 3-D data sets, both are time intensive. This increased time translates into high cost. Neither ultrasound or breast MR imaging involve ionizing radiation, which is an advantage, however, neither of these technologies can identify microcalcifications, a common early warning sign of breast cancer.